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A relatively higher intraocular pressure set at the end of vitrectomy is associated with a more stable and rapid visual recovery for patients with vitreous haemorrhage 期刊论文

编号：

000F7D40A48988ADBB16804F69B628C7
作者：

Zhou, Chuandi#^[1]Zhang, Zhenzhen#^[2]Luo, Dawei#^[1]Gu, Chufeng^[1];Lahm, Tashi^[3];Draga, Deji^[3];Qiu, Qinghua(邱庆华)*^[1,3]
语种：

英文
期刊：

ACTA OPHTHALMOLOGICA ISSN：1755-375X 2020 年 ; JUN
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关键词：

intraocular pressure (IOP) pars plana vitrectomy (PPV) recurrence vitreous haemorrhage (VH)
摘要：

Purpose To compare structural and functional improvements in patients with vitreous haemorrhage (VH) with different IOPs re-established at the end of pars plana vitrectomy (PPV). Methods It is a prospective, randomized, comparative, interventional study. Ninety-five patients with nonclearing VH were randomized to receive PPV with normalized IOPs of 15 mmHg (Group I: 32 eyes), 25 mmHg (Group II: 32 eyes) and 35 mmHg (Group III: 31 eyes) at the end of surgery. The grade of vitreous opacity and best-corrected visual acuity (BCVA) on postoperative day 1, week 1, month 1 and month 3 were compared with a mixed model for repeated measures analysis. Results All 3 groups achieved significant improvement on postoperatively in BCVA (p < 0.01) and vitreous opacity (p < 0.01) compared with the baseline. The group difference was significant at the end of week 1 and showed a trend of higher IOP set at the end of PPV with better anatomical (p < 0.01) and visual recovery (p < 0.01). However, at postoperative month 1 and month 3, equivalent anatomical (month 1: p = 0.56; month 3: p = 0.36) and visual outcomes (month 1: p = 0.16; month 3: p = 0.88) were obtained in the 3 groups. The average effect of IOP on BCVA (group II versus group III: effect size (ES): 0.41, p < 0.01; group I versus group III: ES: 0.66, p < 0.01) and vitreous opacity (group II versus group III: ES: 0.70, p < 0.01; group I versus group III: ES:1.09, p < 0.01) over the course of the study period was statistically significant. The only postoperative complication was recurrent VH in two patients allocating in group I and II, respectively. Conclusions A relatively higher IOP set at the end of vitrectomy resulted in a more stable and rapid recovery with fewer complications in patients with non-complex VH.
推荐引用方式
GB/T 7714：

Zhou Chuandi,Zhang Zhenzhen,Luo Dawei, et al. A relatively higher intraocular pressure set at the end of vitrectomy is associated with a more stable and rapid visual recovery for patients with vitreous haemorrhage [J].ACTA OPHTHALMOLOGICA,2020.
APA：

Zhou Chuandi,Zhang Zhenzhen,Luo Dawei,Gu Chufeng,&Qiu Qinghua.(2020).A relatively higher intraocular pressure set at the end of vitrectomy is associated with a more stable and rapid visual recovery for patients with vitreous haemorrhage .ACTA OPHTHALMOLOGICA.
MLA：

Zhou Chuandi, et al. "A relatively higher intraocular pressure set at the end of vitrectomy is associated with a more stable and rapid visual recovery for patients with vitreous haemorrhage" .ACTA OPHTHALMOLOGICA(2020).
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